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Lymphoma is a cancer of the lymph nodes and lymphatic system. This cancer may be localized to one particular region, or may spread throughout the entire body. Lymphoma is a relatively common cancer, accounting for 15-20% of new cancer diagnoses in dogs. The prognosis for lymphoma varies, depending on various characteristics that can only be determined by specialized testing.
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The most common forms of cutaneous lymphoma are epitheliotropic lymphoma and dermal lymphoma. No specific risk factors or causes have been identified in the development of cutaneous lymphoma. Generally, cutaneous lymphoma can appear as various-sized irritated, ulcerated, or infected patches anywhere on the skin, including the gums, nose, or lip margins. These areas may become ulcerated and bleed, or become crusted. Secondary infections are possible. By far, the most common treatment for cutaneous lymphoma is chemotherapy. Unfortunately, the response to treatment, although initially encouraging, is typically short-lived, with gradual return of the tumors.
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Ferrets can suffer from tumors in any part of their body, ranging from benign cancers of the skin to aggressive malignant tumors of internal organs. The clinical signs depend on the type of tumor, the organ involved, and the stage of the disease. For a dedicated owner with an otherwise healthy-looking patient, treatment with chemotherapy is a very good option.
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Lysosomal storage diseases are a rare collection of conditions that are inherited. Many of them are more prevalent in certain breeds and are seen in the first few months of life. Clinical signs vary depending on the type of disease, but commonly include failure to thrive, incoordination, vision loss, and seizure. Prognosis is usually poor for long-term survival.
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Bacterial overgrowth is a condition of the small intestine resulting in increased numbers of bowel bacteria. The major concern with bacterial overgrowth is the development of a condition called small intestinal bacterial overgrowth. The bacteria cause damage to the surface of the bowel so digested food cannot be absorbed resulting in malabsorption of nutrients. Malabsorption and SIBO both result in diarrhea but with bacterial overgrowth the diarrhea is chronic. Many cases respond to long term antibiotics.
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There are several different types of malignant mammary tumors, with carcinomas being the most common. Carcinomas arise from epithelial (skin) cells, tubules of the mammary glands, or other cells found in the mammary chain. The size of the masses and their appearance may vary, but they are usually firm and nodular. Occasionally, the skin over the mass may ulcerate (open) and bleed, and the affected area may feel warm to the touch and become painful. Detecting and treating these tumors when they are small, and before spread has occurred, will provide your dog with the best chance for long-term control.
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A mammary tumor develops because of abnormal replication of the cells that make up the breast tissue. In cats, most mammary tumors (80-96%) are malignant. Sexually intact cats have a seven-fold increased risk for mammary tumors compared to spayed cats. Detecting and treating these tumors when they are small, and prior to metastasis, provides your cat with the best chance of long-term control. Surgery is by far the best treatment and, given the high metastatic rate in these tumors, chemotherapy is typically pursued afterward.
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Feral cats are fiercely independent and survive (but may not thrive) without the help of humans. They avoid people and hide, back away, or flee when they spot humans. Lack of immunization, parasite control, adequate nutrition, and hygiene put feral cats at risk of many life-threatening problems. TNR (Trap, Neuter, and Release) programs are the hallmark of controlling feral cat populations.
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Mast cells are a type of white blood cell that plays a large role in allergic response through degranulation. Mast cell tumors (MCT) can occur in the skin, spleen, or gastrointestinal tract of cats. Their cause is unknown; however, many affected cats show a genetic mutation in the KIT protein involved in replication and cell division. Cutaneous MCTs most often appear as hard pale/white plaques or nodules, often around the head and they may be itchy. Splenic MCTs cause decreased appetite, weight loss, and vomiting. Intestinal MCTs may cause GI upset and bloody stools, and a mass may be palpable. Diagnosis is typically achieved via fine needle aspirate although histopathology can be used. Treatment usually requires surgical removal of the masses or the spleen. Sometimes, chemotherapy or radiation is needed.
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Masticatory muscle myositis (MMM) is an immune system disorder in which the dog's immune system identifies the dog's own muscle tissue as foreign and attacks it.